About PRF for Facial Rejuvenation

These combined elements release growth factors which trigger cell reproduction and stimulate tissue regeneration or healing in the treated area.

Platelet Rich Fibrin (or PRF) is created using your own blood. The process begins by a trained health care professional drawing a small amount of blood. A proprietary blend of calcium is added to this blood. This solution is then spun in a centrifuge and separated into parts which include red blood cells, white blood cells and the platelet rich component (PRF). As compared to PRP, the sample is spun more slowly. Adding the proprietary calcium blend allows the PRF to turn to gel once injected into the tissue. This conversion to a more viscous solution prolongs the exposure of the treated area to growth factors.

Once injected into the face, the PRF does its job to support tissue regeneration including collagen stimulation and tissue hydration.

Platelets are small cells in the blood that are involved in the clotting and healing process. When PRF is injected into the skin it creates mild inflammation that triggers the healing cascade. As platelets organize in the treatment area, they release enzymes that promote healing of the tissue by attracting stem cells and growth factors to "repair" the area. This repair process encourages the development of new collagen which repairs damaged aging skin, improves skin texture, provides soft contour, and improves the appearance of scars.

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Who is a candidate for PRF?

Anyone who:

• Has allergies to dermal fillers

• Would prefer a more natural approach

• Would like correction of fine lines and contouring

Anyone looking for a treatment to even out skin tone, improve skin texture, reduce acne scarring, brightening of the under-eye area, and softening of fine lines.  

Platelet Rich Fibrin Matrix provides immediate results using a unique blood-based gel which is injected into areas of the face experiencing volume loss. This product produces long term collagen boosting and skin regenerative effects. Many patients love this treatment as it uses the patients' growth factors and their regenerative properties to address areas of concern.

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Who is NOT a candidate?

Anyone with:

• Acute or chronic infections

• Skin disease (SLE)

• Cancer

• Chemotherapy treatments within the last 12 months

• Severe metabolic or systemic disorders

• Abnormal platelet function (blood disorders)

• Chronic liver pathology

• Anticoagulation therapy

• Systemic use of corticosteroids within 2 weeks of the procedure

Multiple PRF Matrix treatments are required to achieve the desired results. Variations in outcome are expected and depend largely on the quality of sample collected and individual response to the PRF. Improvements are generally visible by 4 weeks and continue to improve gradually for 2-6 months after the last treatment. The current data demonstrates that results may last 18-24 months.

For most people, we start with three to five treatments, four to six weeks apart. The healing/regenerative process of the PRF treatment continues for up to six months after the last treatment. After assessment of your response, a maintenance program of one to three treatments annually would be prescribed.

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PRP vs PRF – what is the difference?

PRF is considered the second generation of platelet concentrations. The first generation is what we call PRP.

Both treatments use a concentration rich in platelets which are obtained in the same manner from the patient. Once the sample is collected PRP and PRF are both spun in a centrifuge, however PRF is spun at a much slower speed to isolate fibrin. Fibrin makes the final product more gel-like as opposed to thin liquid (which is PRP). The fibrin matrix helps intensify and localize growth factors, white blood cells and other factors that stimulate collagen production. PRF treatment is very focused to target areas of concern while PRP diffuses more quickly.

Studies have shown that PRF lasts longer in the tissue than PRP which allows for increased benefit in treatment areas.